Malformations (e.g. knock knees or bow-leggedness), hormonal imbalances (e.g. diabetes), rheumatic conditions and accidents (e.g. torn cruciate ligaments) are some of the major causes of chronic and degenerative arthritis of the knee joint.
Lesions induced by increased wear and tear of the cartilage trigger degenerative processes, which cause the bones of the joint to come into direct contact with one another. This, in turn, leads to growing pain, which persists even with the joint at rest. At the same time, the extent of knee movement becomes severely restricted.